Research Studies at the University of Pittsburgh Asthma Institute
Volunteer for ASTHMA – AIR (Asthma Institute Research Registry)
The University of Pittsburgh Asthma Institute at UPMC/UPSOM aims to improve the understanding and treatment of asthma/allergic diseases and to implement improved approaches throughout the asthma community. A centerpiece of the Asthma Institute is the Volunteer for Asthma program, a group of interested patients with asthma, who wish to be notified of new research studies for which they may qualify. Registry patients participate in the collection of information about their disease, including basic screening questions, lung function testing, and a blood sample. Registry patients have enabled the Asthma Institute to be a national leader in the discovery of new treatment options for patients with asthma. The Asthma Institute is currently looking for individuals over 18 years of age with a current diagnosis of asthma who do not smoke. No more than an hour and a half of your time is needed to join Volunteer for ASTHMA – AIR and you will be compensated $20 plus parking. For more information, call 1-866-804-5278 or email email@example.com.
THE ASTHMA INSTITUTE IS CURRENTLY RECRUITING FOR THE FOLLOWING STUDIES:
Investigational ASTHMA Drug Studies
If you are experiencing asthma symptoms such as shortness of breath, wheezing, chest tightness, or coughing and have been taking medication to try to manage your symptoms, you may want to consider participating in a clinical research study.
The research study is examining the safety, tolerability, and effectiveness of a new investigational study drug for asthma.
You may be eligible for the study if you:
- Are between 18 and 65 years of age
- Have had asthma symptoms for at least 1 year
- Have never smoked or have been a non-smoker for 1 year or longer
All qualified study participants will receive the study-related drugs and tests and procedures at no charge. Participants may be compensated for travel to and from clinic visits. Your asthma condition will be closely monitored during the study. There are important things you should know about the potential benefits and risks of participating that the study doctor will explain to you. To learn more, and to find out if the study may be an option for you, please call the Asthma Institute at 1-866-804-5278. Please refer to the “Merck Study” when calling.
If you are:
- At least 18 years of age
- Have moderate to severe asthma for at least 12 months, that is not fully controlled
- Currently treated with daily controller medications for asthma such as Advair, Symbicort or Dulera
- Without serious health problems
You may qualify to participate in an asthma research study.
Qualified participants will receive:
- Study related medical exams
- Study related investigational medication
For more information, and to find out if the study may be an option for you, please call the Asthma Institute at 1-866-804-5278. Please refer to the “SANOFI Study” when calling.
Non-Investigational Drug Studies
Researchers at the University of Pittsburgh Asthma Institute are looking for volunteers to participate in an asthma research study to collect biological samples.
If you are a non-smoking adult between the ages 18-60 with or without a diagnosis of asthma and otherwise in good health, you may be eligible to participate.
The study includes 3-6 office visits at Montefiore Hospital located in Oakland. All study related procedures, including bronchoscopy and lung function evaluations, blood tests and breathing tests will be performed at no cost. A bronchoscopy is a procedure that involves passing a flexible tube (a bronchoscope) through your mouth and into your lungs. If you qualify you may be compensated for your time and travel.
For more information call the University of Pittsburgh Asthma Institute at 1-866-804-5278. Please refer to the "Microbiome Study" when calling.
SARP III Study
Currently, Dr. Wenzel is looking for men and women who are:
- 18 and older
- physically healthy, except for a diagnosis of asthma
- tobacco free
The research study involves visits over a 4 – 6 week period plus follow-up:
- Lung Function Evaluations
- Blood Tests
- Allergy Testing
- Breathing Tests
- Bronchoscopy - a procedure performed by a doctor that involves passing a flexible tube (a bronchoscope) through your mouth and into your lungs. This procedure can be performed easily and safely under moderate sedation.
Compensation and parking provided. To learn more, call 1-866-804-5278 and refer to the “SARP III Study”.
EFADA (Electrophilic fatty acid derivatives in asthma)
We are looking for volunteers to participate in an asthma research study to collect biological samples. If you are between the ages of 18 and 60, do not currently smoke, have a diagnosis of asthma, and are otherwise in good health, you may be eligible to participate. Subjects with a mild to moderate asthma diagnosis will be asked to participate in this study. Participation will be for approximately 2 weeks (3-4 office visits) however, the time may vary depending on scheduling conflicts.
All office visits are conducted at UPMC Montefiore Hospital located in Oakland. All study related procedures, including two bronchoscopies and lung function evaluations, blood tests and breathing tests will be performed at no cost. If you qualify you may be compensated up to $530 for your time and travel. To learn more, contact The Asthma Institute at 1-866-804-5278.
Dr. Fernando Holguin at the University of Pittsburgh Asthma Institute is seeking volunteers for an asthma research study to learn how weight and a dietary supplement typically found in watermelon (Citrulline) may relate to asthma.
You may be eligible to participate if you are:
- between the ages of 18 and 75
- do not currently smoke
- have a diagnosis of asthma
- overweight (a body mass index of 30 or greater
- generally in good health
Study includes 3-4 office visits at UPMC Montefiore Hospital located in Oakland. All study related procedures, including lung function evaluations, blood tests and breathing tests will be performed at no cost. Participation does not require changing your current asthma regime. Compensation up to $115 is provided for your time and travel. To learn more, contact The Asthma Institute at 1-866-804-5278 and refer to the “SANDIA Study”.
UPMC is conducting a research study to learn more about asthma and the treatment of asthma in children. We are looking for children with asthma aged 6 – 17 who are physically healthy. Study participants will be followed up to 3.5 years and will undergo:
- Lung function evaluations
- Blood and urine tests
In addition, research study participants will receive a physical exam, a steroid shot for asthma, and will be asked to complete various asthma questionnaires. The research study includes:
- 8 visits, which will be held at Children’s Hospital of Pittsburgh of UPMC
- Up to 8 follow-up phone calls
Participants will be compensated for their time and parking will also be provided at no cost. To learn more, please call Paul Rebovich at 412-692-5873 or email Paul.Rebovich@chp.edu.
INFANT/AVICA (Individualized Therapy for Asthma in Toddlers)/ (Acetaminophen versus Ibuprofen in Children with Asthma)
The purpose of this research study is to find out if one asthma treatment works better than another in toddlers. Another purpose is to see if there is something about a child that help doctors predict which treatment would work better.
It is possible that medications used to treat fever or body aches such as acetaminophen and ibuprofen work differently in children with Asthma. There is a study looking at this question and is call the AVICA study. If you join the INFANT study, you must also join the AVICA study.
Children’s Hospital of Pittsburgh of UPMC is one of 9 clinical centers in the country doing this study. Children invited to participate in these studies must be between 12-59 months (1 year to almost 5 years old) and is healthy other than having asthma.
A child participating in this research study will undergo physical exams, questionnaires, blood, urine and nasal mucus sampling, and asked to complete a symptom diary. This study has 8 scheduled visits and 6 scheduled study phone calls. Study participation will last up to 13 months. For more information please call Katie at 412-692-8929.